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Adipotide (FTTP)

Proapoptotic Peptide Targeting Adipose Vasculature

Fat-targeting proapoptotic peptide studied in primate adiposity models by Arap & Pasqualini. Available in 5 mg and 10 mg research vials.

Fat Loss / Metabolic

Category

From $80.99

Price

Research

Grade

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Adipotide (FTTP)

Price

From $80.99

✓ 10% off via PeptidesMuscle

Suggested Protocol

Short-arc rodent scaling: 1-2 mg/kg/day SC for 7-10 days, with serial BUN, creatinine, and ideally KIM-1/NGAL measurements at baseline, day 5, and day 10. For 28-day primate-replication endpoints use the 10mg vial. The 5mg format is not intended for inexperienced Adipotide protocols — renal-monitoring infrastructure should be in place before starting.

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ApoptosisAdiposeProapoptotic

The reason this compound exists in two vial sizes is not convenience — it is renal exposure. Barnhart et al. (2011) saw dose-dependent proximal tubule accumulation of the (KLAKLAK)₂ warhead in the same dosing range that produced primate weight loss. Serious Adipotide research protocols build renal function (BUN, creatinine, KIM-1, NGAL) into the primary endpoint set, and the 5mg vial is designed around that constraint. Half the inventory = half the window between renal screening intervals = tighter experimental control.

Documented Effects

Half-inventory vial for short-arc (7-10 day) Adipotide research

Matches the constrained window between renal-function screening intervals

Same CKGGRAKDC-(KLAKLAK)₂ fusion chemistry as the 10mg format

Supports approximately one 350g rodent subject for 10 days at 1-2 mg/kg/day

Designed for mechanistic endpoints, not full 28-day weight-loss replications

Renal-monitoring-integrated research planning assumed

Format Rationale

Why Half the Inventory Is Sometimes Correct

The 5mg vial is not simply the "cheaper option." It is sized for research arcs where the experimental design deliberately ends before the renal-monitoring window closes. Running the 10mg full-cycle inventory when the protocol is only 10 days long creates temptation to extend the study past its renal-safety design — a temptation the 5mg format removes by simply running out of compound at the right time.

Renal-Monitoring Interval

What 7-10 Days of Dosing Actually Looks Like

Baseline BUN/creatinine, initiate daily SC dosing at 1-2 mg/kg/day, re-measure at day 5 for early tubule-injury signal, continue to day 10 with final endpoint measurements including KIM-1 or NGAL if available. MRI or DEXA measurement of white-adipose volume at baseline and endpoint. If renal markers drift upward at day 5, the protocol terminates — the 5mg vial ensures this decision is tied to data, not to "running out of research inventory."

Format Selection Logic

When to Choose 5mg Over 10mg

Choose 5mg when the research question is a short-arc mechanistic endpoint (early vasculature response, dose-response characterization at fixed short timeframe, PD marker development). Choose 10mg when the research question is a full Barnhart replication (28-day endpoint, total body-weight loss as primary outcome, long-arc MRI vascular-regression imaging). The choice is about research design, not about budget.

Specifications

ProductAdipotide (FTTP)
CategoryFat Loss / Metabolic
FormatLyophilized powder
PriceFrom $80.99

Standard Protocol

Short-arc rodent scaling: 1-2 mg/kg/day SC for 7-10 days, with serial BUN, creatinine, and ideally KIM-1/NGAL measurements at baseline, day 5, and day 10. For 28-day primate-replication endpoints use the 10mg vial. The 5mg format is not intended for inexperienced Adipotide protocols — renal-monitoring infrastructure should be in place before starting.

Complementary Compounds

tesofensine-2mg
slu-pp-332-10mg
Adipotide (FTPP) 10mg

Adipotide (FTPP) 10mg

Fat Loss / Metabolic

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Adipotide (FTTP) — FAQs

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