Adipotide (FTTP)
Proapoptotic Peptide Targeting Adipose Vasculature
Fat-targeting proapoptotic peptide studied in primate adiposity models by Arap & Pasqualini. Available in 5 mg and 10 mg research vials.
Fat Loss / Metabolic
Category
From $80.99
Price
Research
Grade

Price
From $80.99
✓ 10% off via PeptidesMuscle
Suggested Protocol
Short-arc rodent scaling: 1-2 mg/kg/day SC for 7-10 days, with serial BUN, creatinine, and ideally KIM-1/NGAL measurements at baseline, day 5, and day 10. For 28-day primate-replication endpoints use the 10mg vial. The 5mg format is not intended for inexperienced Adipotide protocols — renal-monitoring infrastructure should be in place before starting.
The reason this compound exists in two vial sizes is not convenience — it is renal exposure. Barnhart et al. (2011) saw dose-dependent proximal tubule accumulation of the (KLAKLAK)₂ warhead in the same dosing range that produced primate weight loss. Serious Adipotide research protocols build renal function (BUN, creatinine, KIM-1, NGAL) into the primary endpoint set, and the 5mg vial is designed around that constraint. Half the inventory = half the window between renal screening intervals = tighter experimental control.
Documented Effects
Half-inventory vial for short-arc (7-10 day) Adipotide research
Matches the constrained window between renal-function screening intervals
Same CKGGRAKDC-(KLAKLAK)₂ fusion chemistry as the 10mg format
Supports approximately one 350g rodent subject for 10 days at 1-2 mg/kg/day
Designed for mechanistic endpoints, not full 28-day weight-loss replications
Renal-monitoring-integrated research planning assumed
Format Rationale
Why Half the Inventory Is Sometimes Correct
The 5mg vial is not simply the "cheaper option." It is sized for research arcs where the experimental design deliberately ends before the renal-monitoring window closes. Running the 10mg full-cycle inventory when the protocol is only 10 days long creates temptation to extend the study past its renal-safety design — a temptation the 5mg format removes by simply running out of compound at the right time.
Renal-Monitoring Interval
What 7-10 Days of Dosing Actually Looks Like
Baseline BUN/creatinine, initiate daily SC dosing at 1-2 mg/kg/day, re-measure at day 5 for early tubule-injury signal, continue to day 10 with final endpoint measurements including KIM-1 or NGAL if available. MRI or DEXA measurement of white-adipose volume at baseline and endpoint. If renal markers drift upward at day 5, the protocol terminates — the 5mg vial ensures this decision is tied to data, not to "running out of research inventory."
Format Selection Logic
When to Choose 5mg Over 10mg
Choose 5mg when the research question is a short-arc mechanistic endpoint (early vasculature response, dose-response characterization at fixed short timeframe, PD marker development). Choose 10mg when the research question is a full Barnhart replication (28-day endpoint, total body-weight loss as primary outcome, long-arc MRI vascular-regression imaging). The choice is about research design, not about budget.
Specifications
| Product | Adipotide (FTTP) |
|---|---|
| Category | Fat Loss / Metabolic |
| Format | Lyophilized powder |
| Price | From $80.99 |
Standard Protocol
Short-arc rodent scaling: 1-2 mg/kg/day SC for 7-10 days, with serial BUN, creatinine, and ideally KIM-1/NGAL measurements at baseline, day 5, and day 10. For 28-day primate-replication endpoints use the 10mg vial. The 5mg format is not intended for inexperienced Adipotide protocols — renal-monitoring infrastructure should be in place before starting.
Complementary Compounds
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Adipotide (FTTP) — FAQs
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