Pinealon
Khavinson Tripeptide (Glu-Asp-Arg)
Short synthetic tripeptide studied by the Khavinson group for neuroprotection and cognitive-aging endpoints. Available in 10 mg and 20 mg.
Anti-Aging & Longevity
Category
From $62.99
Price
Research
Grade
Price
From $62.99
✓ 10% off via PeptidesMuscle
Suggested Protocol
Within-framework Khavinson cadence: 10-day courses at 100–300 mcg/day, typically subcutaneous or intramuscular. Sublingual is also described. A 10mg vial supports a single full course at these research doses.
Pinealon is not in the same pharmacological family as Selank or Semax, despite being shelved alongside them in "nootropic" catalogues. It is a Khavinson short-peptide bioregulator with the sequence Glu-Asp-Arg (EDR), derived from the broader polypeptide preparation Cortexin and positioned within the Khavinson framework as the brain-tissue tripeptide representative. That framework proposes tissue-specific transcriptional modulation via short-peptide DNA binding — a hypothesis developed primarily within the St. Petersburg Institute of Bioregulation and Gerontology and not independently replicated outside it.
Specifications
| Product | Pinealon |
|---|---|
| Category | Anti-Aging & Longevity |
| Format | Lyophilized powder |
| Price | From $62.99 |
Classification
Wrong Shelf for a Conventional Nootropic
Pinealon is a Khavinson bioregulator tripeptide. Evaluating it with the same benchmarks used for Selank, Semax, or racetams misrepresents the framework it was designed within. Its claim is tissue-specific transcriptional modulation, not monoaminergic or GABAergic modulation.
Endpoint Profile
Cortical and Hippocampal Tissue, Not Pineal
The literature covers aged-rodent cortical and hippocampal endpoints: apoptosis markers, mitochondrial membrane potential, cognitive-task performance in aged animals. Pinealon is the cerebrum-positioned peptide in the Khavinson framework; Epitalon is the pineal-positioned one. The name causes confusion.
Evidence Tier
Within-Framework, Not Independently Replicated
As with most Khavinson short-peptide bioregulators, the body of evidence is largely published by the St. Petersburg Institute of Bioregulation and Gerontology and affiliated groups. Researchers evaluating the framework should read Pinealon data inside that context rather than as free-standing Western-style pharmacology.
Documented Effects
Khavinson EDR (Glu-Asp-Arg) tripeptide — not a Selank/Semax-class nootropic
Brain-tissue-positioned within the bioregulator framework
Endpoints cover ROS, mitochondrial potential, and aged-rodent cognitive rescue
Distinct from Epitalon (pineal/telomerase) despite the name overlap
Standard 10-day-course vial size
Lyophilised with batch COA
Dosing Guide
Within-framework Khavinson cadence: 10-day courses at 100–300 mcg/day, typically subcutaneous or intramuscular. Sublingual is also described. A 10mg vial supports a single full course at these research doses.
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