Epitalon
Khavinson Tetrapeptide — Ala-Glu-Asp-Gly
Four-residue synthetic peptide derived from Epithalamin, the pineal extract characterized by Khavinson. Available in 10 mg and 50 mg vials.
Anti-Aging & Longevity
Category
From $53.99
Price
Research
Grade
Price
From $53.99
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Suggested Protocol
Canonical Khavinson Epitalon course: 10 consecutive days at 100–500 mcg/day SC or IM, followed by a washout of 3–6 months before the next course. Sublingual routes are also described. A 10mg vial covers one full course at the upper end of the daily range with reconstitution overhead.
Epitalon is the Ala-Glu-Asp-Gly tetrapeptide synthesised by Vladimir Khavinson's group in St. Petersburg as the short-peptide representative of the bovine pineal gland extract Epithalamin. The synthesised tetrapeptide was proposed to carry the transcriptionally active fragment of Epithalamin into a controllable, single-molecule research tool — with claimed telomerase-activating activity in Khavinson-published cell culture work (somatic human fibroblast lineages, as well as rodent pineal-gland models).
Specifications
| Product | Epitalon |
|---|---|
| Category | Anti-Aging & Longevity |
| Format | Lyophilized powder |
| Price | From $53.99 |
Canonical Course Fit
Why 10mg Is the One-Cycle Vial
The standard Russian primary literature Epitalon course is 10 days at a few hundred micrograms per day. The arithmetic of that course sits cleanly inside a 10mg vial. Researchers who want to do a single faithful replication of that literature, for a single subject or animal, have the right vial size in 10mg. More ambitious designs step up.
Evidence Footprint
In-Vitro Telomerase Signal Is the Flagship Claim
The most-cited Epitalon result is telomerase activation in cell-culture work from Khavinson and collaborators, observed in human somatic fibroblast lineages among other systems. Some independent senescence-marker corroboration exists. The compound remains outside the mainstream telomerase-biology canon of validated activators; researchers should frame it as within-framework evidence and design experiments accordingly.
Lineage Note
Tetrapeptide Representative of Epithalamin
Epithalamin was a bovine pineal extract used in Soviet/post-Soviet clinical research for decades. Epitalon is the synthesised short-peptide representative of that extract's proposed active fraction. The extract is not the same as the peptide — that lineage distinction matters when reading mixed literature.
Documented Effects
Single-course Khavinson Epitalon vial
Ala-Glu-Asp-Gly tetrapeptide synthesised to represent Epithalamin activity
10mg fits a standard 10-day course at 100–500 mcg/day with reconstitution headroom
Appropriate for one-subject replication of canonical Russian primary literature
Step up to 50mg for multi-animal or multi-course designs
Lyophilised Phiogen preparation with batch COA
Dosing Guide
Canonical Khavinson Epitalon course: 10 consecutive days at 100–500 mcg/day SC or IM, followed by a washout of 3–6 months before the next course. Sublingual routes are also described. A 10mg vial covers one full course at the upper end of the daily range with reconstitution overhead.
Epitalon — FAQs
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