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Clinical Evidence|STEP-1 Trial (2021)·14.9% avg. body weight reduction·68 weeks
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Fat Loss / MetabolicGLP-1Weight ManagementWeight Management

Semaglutide

GLP-1 Receptor Agonist — Weekly Dosing

Long-half-life GLP-1 receptor agonist studied in the STEP weight-management trials. Available in five vial sizes from 3 mg through 30 mg to match research-protocol duration; all sizes draw from the same batch and CoA.

14.9%

Body Wt. Loss

~7 days

Half-Life

Once weekly

Dosing

10% OFF
Semaglutide

Price

From $44.99

✓ 10% off via PeptidesMuscle

Suggested Protocol

The STEP-1 onboarding tiers: 0.25mg weekly for weeks 1–4, then 0.5mg weekly for weeks 5–8. One 3mg vial covers both tiers with ~0.75mg of headroom for reconstitution loss. A researcher who completes both tiers and intends to continue to the 1.0mg tier typically transitions to the 12mg mid-arc vial from week 9 onward.

3rd-Party Tested·CoA Verified·Fast Ship
GLP-1Weight ManagementSTEP Trials

The 3mg vial is the smallest semaglutide size, sized deliberately for researchers who have not committed to a full protocol arm yet. The STEP-1 titration schedule opens with four weeks at 0.25mg weekly to assess tolerability before escalation — gastrointestinal side effects (nausea, early satiety, delayed gastric emptying discomfort) tend to surface at this tier and determine whether a subject can proceed. A 3mg vial covers those first four weeks with headroom, and extends through the first 0.5mg tier (weeks 5–8) as well. Twelve weeks of onboarding, one vial.

Specifications

ProductSemaglutide
CategoryFat Loss / Metabolic
FormatLyophilized powder
PriceFrom $44.99

Key Trial Data

TrialSTEP-1 Trial (2021)
Outcome14.9% avg. body weight reduction
Duration68 weeks

Study-Observed Effects

Covers the full 0.25mg and 0.5mg titration tiers (~weeks 1–8 of STEP-1)

Matches pilot-study and tolerability-assessment economics without wasted peptide

Lowest entry cost for a researcher evaluating whether semaglutide fits a research question

Supports single-subject acute pharmacodynamic probing at sub-maintenance doses

Avoids stability-window pressure that larger vials impose on slow-consumption research

Entry-tier pricing for proof-of-concept arms before committing to maintenance-scale vials

Research Protocol

The STEP-1 onboarding tiers: 0.25mg weekly for weeks 1–4, then 0.5mg weekly for weeks 5–8. One 3mg vial covers both tiers with ~0.75mg of headroom for reconstitution loss. A researcher who completes both tiers and intends to continue to the 1.0mg tier typically transitions to the 12mg mid-arc vial from week 9 onward.

Semaglutide — FAQs

Further Reading

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