Semaglutide 15mg
Maximum Dose — Long-Term Maintenance Format
The maximum volume format — 15mg matches the complete STEP trial maintenance dose (2.4mg weekly × 6 weeks+). Best value per mg for serious long-term research protocols.
Starting From
$159.99
Sold By
Apollo Peptide Sciences
Suggested Protocol
For researchers at established maintenance dose of 1.7–2.4mg weekly. Reconstitute with 1.5–2ml bacteriostatic water. SubQ injection once weekly at consistent intervals for stable plasma levels. Store refrigerated; use within 28 days of reconstitution.
14.9%
Body Wt. Loss
6+ wks
Duration
15 mg vial
Format
The Long Game: What Consistent Semaglutide Dosing at Full Strength Actually Produces
The 15mg semaglutide vial is engineered for the serious long-term researcher: it provides the maximum vial volume available, delivers the lowest cost per milligram across all three semaglutide formats, and contains enough compound to sustain the maximum 2.4mg weekly maintenance dose — exactly as used in the STEP trials — for more than six weeks of uninterrupted research.
The STEP trial program's pivotal 2.4mg weekly maintenance dose is the reference standard for semaglutide's full therapeutic potential. Achieving and sustaining this dose is where the 14.9% average body weight reduction data was generated. The 15mg vial is precisely sized for this phase — not dose escalation, not experimentation, but full-scale maintenance-phase research where the compound's metabolic and body composition effects are most completely expressed.
At the 2.4mg weekly maintenance dose, semaglutide's hypothalamic GLP-1 engagement is at maximum intensity: appetite suppression is profound and consistent, gastric emptying is significantly slowed, and the hormonal environment driving fat mobilization is continuously maintained between weekly injections. The 15mg vial's supply duration at this dose — approximately 6 weeks — aligns with the natural assessment intervals for body composition response.
For cost-conscious researchers running multi-month protocols, the 15mg vial offers the most rational economics: a single vial costs less per milligram than any other semaglutide format in the Apollo catalog. Combined with the logistical simplicity of fewer vials to manage, reconstitute, and track, the 15mg format is the standard choice for established, ongoing semaglutide research.
The STEP-1 Reference Dose
2.4mg Weekly: Where the 14.9% Average Weight Reduction Was Generated
The STEP-1 trial's landmark 14.9% average body weight reduction over 68 weeks was produced at the 2.4mg weekly maintenance dose — the same dose this 15mg vial is designed to support. At 2.4mg weekly, hypothalamic GLP-1 receptor engagement is at maximum consistent intensity: hunger signals are substantially suppressed around the clock, gastric emptying is meaningfully slowed at every meal, and insulin sensitivity improvements are fully established. Below this dose, some of these effects are partial. At 2.4mg, they're complete — and the 15mg format is precisely calibrated to run there for 6+ uninterrupted weeks.
What Changes Over Months
Semaglutide's Effects Compound Over Time in Ways Week-4 Results Don't Show
The first 4–6 weeks of semaglutide produce the initial adaptation and early fat loss as caloric intake drops. But the cumulative effects over months go deeper: the gut microbiome adapts to the changed eating patterns, food preferences shift (high-calorie foods become less appealing as the reward signaling around food dampens), and metabolic improvements in glucose handling and lipid profiles become measurable. The 14.9% average weight reduction wasn't achieved in the first 8 weeks — it accumulated over 68 weeks of sustained dosing. Long-format supply like the 15mg vial is the practical foundation for multi-month commitment.
Best Value Logic
When Cost Per Milligram Becomes the Right Metric — and When It's the 15mg Vial
At maintenance dosing (2.4mg weekly), you're consuming semaglutide continuously. The math compounds: purchasing multiple 5mg vials to cover the same period costs significantly more per milligram than a single 15mg vial. For researchers in the exploratory phase, the 5mg vial is appropriate — you don't know yet if you'll complete the protocol. For researchers who have confirmed tolerability, established their maintenance dose, and are committed to multi-month research, the 15mg vial's per-milligram economics are the strongest argument for using it. Commitment to the protocol is the prerequisite; the 15mg is the supply format that reflects that commitment.
Key Benefits
Lowest cost per milligram across all three semaglutide vial sizes
Matches the 2.4mg weekly STEP trial maintenance dose for 6+ weeks
Optimal for established protocols at full therapeutic maintenance dosing
Fewer vials to manage for multi-month research programs
Maximum uninterrupted supply duration — avoids mid-protocol gaps
Full expression of semaglutide's appetite suppression and metabolic effects
Ideal for researchers who have completed escalation and confirmed tolerability
Best format for comparing long-term body composition outcomes across time
Full Protocol
For researchers at established maintenance dose of 1.7–2.4mg weekly. Reconstitute with 1.5–2ml bacteriostatic water. SubQ injection once weekly at consistent intervals for stable plasma levels. Store refrigerated; use within 28 days of reconstitution.
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Semaglutide
The compound behind Ozempic/Wegovy. GLP-1 receptor agonist producing significant appetite suppression, fat loss, and metabolic improvement with once-weekly dosing.
